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E.NegidaY.CadriS.et al (2024)

The explanation for this discrepancy can be found in recent papers showing that some cancer cell linesincluding HCT116are not affected by L-BSO or GSH synthesis inactivation because they can compensate GSH depletion by the thioredoxin (TXN) pathway 25 , and by maintaining protein homeostasis through deubiquitinating enzymes (DUB) 32

Figure 2 Bioavailability Enhancement: A hallmark of PPR is its ability to augment the bioavailability of drugs and nutrients

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Its not worth taking a product that contains substances that stop you benefiting from the nutrient you are supplementing