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There were no serious adverse events related to treatment or drug discontinuations

The standard volume of a commercially available can of energy drink (250 mL) usually contains 80 mg of caffeine, while the amount of this compound in a 500 mL can or bottle is already 160 mg [20,21]

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Interrogation of the ATM data revealed specific proinflammatory transcripts, including the interferon response genes Gbp3 and Mx2 , CXCL chemokine family members ( Cxcl19 , Cxcl11 , Cxcl10 ), and C-C motif chemokine ligand 5 ( Ccl5 ), that were commonly upregulated in PAR2 mutants when compared with PAR2-WT mice (Supplemental Figure 7B)

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