Because large randomized human trials have not been completed
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As a result, determining the prevalence of extra-esophageal symptoms in GERD patients without typical symptoms is more difficult, as diagnosing these cases is challenging
Lazic D, Sagare AP, Nikolakopoulou AM, Griffin JH, Vassar R, Zlokovic BV
PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis